Uruguay defender Joaquin Piquerez was stretchered off for Uruguay after he suffered a nasty injury against England.
With a little over ten minutes played in the 1-1 draw at Wembley Stadium, the defender battled for the ball against Noni Madueke.
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He knocked the ball out for an England corner, but then went down on the turf in visible pain.
Piquerez needed treatment on the pitch with what appears to be an ankle injury and the match was paused as a result of the incident.
Medical staff eventually got him on a stretcher and took him off, with Jose Maria Gimenez the man to replace him.
The Palmeiras full-back will be hoping to be named in the Uruguay squad for this summer’s World Cup.
However, the injury on Friday night may have scuppered his chances.
Madueke was also an early substitution as he went down injured in a separate incident, with Jarrod Bowen coming on in his place.
Seven minutes were added onto the end of the first half following the injuries.
Late penalty denies England win
With ten minutes to play, it looked as though the match would end in a 0-0 draw that did little to spark excitement.
Ben White ensured this result was avoided as he scored his first ever goal for England with a simple back-post tap-in.
The defender was booed by some Three Lions fans when came on as a substitute following his shock squad recall.
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White made himself unavailable for England in 2024 after a reported fall-out with former assistant Steve Holland.
He was on course to be the saviour at Wembley, but then conceded a late penalty to overshadow his goal.
Federico Valverde was tasked with the spot-kick and smashed it past debutant James Trafford.
England have the opportunity to produce a much more impressive performance on Tuesday night when they face Japan.
It will be their final opportunity to make a statement before making their way to the United States for the World Cup.
